![]() ![]() ![]() As a rule, plasmids from the same group should not be co-transformed, so if you need two plasmids for an experiment, make sure they have "compatible" ori's. This is a free resource for the scientific community that is compiled by Addgene. Generally speaking, plasmids with the same ori are incompatible because they will compete for the same machinery, creating an unstable and unpredictable environment. pUC19 Vector Database Welcome to Vector Database Vector database is a digital collection of vector backbones assembled from publications and commercially available sources. In other words, the best choice of ori depends on how many plasmid copies you want to maintain, which host or hosts you intend to use, and whether or not you need to consider your plasmid's compatibility with one or more other plasmids.
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